Why everyone is suddenly putting salmon sperm on their face

PDRN has entered the chat, and your routine, with big glow-up energy and science-backed value

22 January, 2026
Why everyone is suddenly putting salmon sperm on their face

Salmon sperm in skincare sounds like a prank your group chat would dare you to Google. But lately, it’s everywhere: from K-beauty favourites to Instagram Reels to serum labels that actually look serious. The ingredient in question is PDRN, and it’s quickly becoming the quiet overachiever of the skincare world.

Well, this isn’t just another viral moment. PDRN has been around in dermatology for years, especially for skin healing and repair. Now, as everyone moves away from harsh actives and towards calm, resilient skin, this niche ingredient is finally having its long-overdue glow-up moment.

What is PDRN?

PDRN stands for Polydeoxyribonucleotide, which is basically a DNA extract derived from salmon sperm. Before you cringe too hard, know this: it’s highly purified, lab-processed and safe for skin use. Salmon DNA is used because it is very similar to human DNA, which helps the skin accept it easily, with minimal or no side effects.

In skincare terms, PDRN is all about repair. It helps boost cell regeneration, supports collagen and improves overall skin recovery. Dermats and skincare enthusiasts love it for calming irritated skin and helping it bounce back stronger after damage.

What does it actually do for your skin?

PDRN works quietly in the background. It doesn’t exfoliate, sting or give instant glass skin. Instead, it strengthens the skin barrier, reduces inflammation and improves texture over time. Think healthier skin, not dramatic overnight results.

It is especially popular with sensitive, acne-prone or post-procedure skin. If your face is tired of being attacked by actives, PDRN feels like a soft reset as it is gentle, steady and surprisingly effective.


 

Why is the youth obsessed right now?

Part of the hype comes from Korea, where PDRN treatments have been mainstream for a while. Add TikTok and Instagram explanations, aesthetic clinic content and a growing interest in skin longevity, and K-beauty in particular, and suddenly salmon sperm sounds less weird and more futuristic.

There is also a mindset shift happening. Perfect skin is out, functional skin is in. PDRN fits right into that slow skin era, as it is focused on healing and long-term glow rather than quick fixes.

Here are the PDRN skincare products everyone’s talking about, and you should too:

Dr Reju-All Advanced PDRN Rejuvenating Cream, ₹2,799


Anua PDRN Hyaluronic Acid Capsule 100 Serum, ₹2,100


Innisfree Retinol Green Tea PDRN Skinbooster Toner, ₹1,600


The Face Shop PDRN Deep Hydration Serum, ₹1,820


Minimalist Copper Peptide + PDRN 1.25% Face Serum, ₹699


Foxtale Cell Renewal Collagen-PDRN Serum, ₹695


RENEE Pink Therapy PDRN Pink Peptide Serum, ₹599


Lead image: Getty Images

Inside images: The brands

Also read: The best active-infused cleansers that will simplify the rest of your routine

Also read: Pudding pot blushes are here to give your cheeks a plump, juicy upgrade

Comment